Carolinas Core Concepts Core Concepts in EM; a repository for Carolinas lecture summaries.

2Nov/110

Reversal of Anti-Coagulation

Chelsea Kolshak, MD

  • Warfarin + Life-Threatening Bleed
    • Start FFP early
      • 15 mL/kg IV
      • Type and cross and thawing takes a long time
      • Start it before you get the inr back if you have a high index of suspicion
    • Supplement with Vitamin K 10 mg IV over slow infusion
  • Digatroban has currently no proven reversal agent
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